He is best known for his early and original breakthroughs in surgery as well as for his famous Medical Encyclopaedia called Al-Tasrif, which is composed of thirty volumes covering different aspects of medical science. The more important part of this series comprises three books on surgery, which describe in detail various aspects of surgical treatment as based on the operations performed by him, including cauterization, removal of stone from the bladder, dissection of animals, midwifery, styptics, and surgery of eye, ear and throat. He perfected several delicate operations, including removal of the dead foetus and amputation.
Al-Tasrif was first translated by Gherard of Cremona into Latin in the Middle Ages. It was followed by several other editors in Europe . The book contains numerous diagrams and illustrations of surgical instruments, in use or developed by him, and comprised a part of the medical curriculum in European countries for many centuries. Contrary to the view that the Muslims fought shy of surgery, Al-Zahrawi's Al-Tasrif provided a monumental collection for this branch of applied science.
Al-Zahrawi was the inventor of several surgical instruments, of which three are notable:
In his book Al-Tasrif, Al-Zahrawi has also discussed the preparation of various medicines, in addition to a comprehensive account of surgical treatment in specialized branches, whose modern counterparts are E.N.T., Ophthalmology, etc. In connection with the preparation of medicines, he has also described in detail the application of such techniques as sublimation and decantation. Al-Zahrawi was also an expert in dentistry, and his book contains sketches of various instruments used thereof, in addition to a description of various important dental operations. He discussed the problem of non-aligned or deformed teeth and how to rectify these defects. He developed the technique of preparing artificial teeth and of replacement of defective teeth by these. In medicine, he was the first to describe in detail the unusual disease, haemophilia.
There can be no doubt that Al-Zahrawi influenced the field of medicine and surgery very deeply and the principles laid down by him were recognized as authentic in medical science, especially surgery, and these continued to influence the medical world for five centuries. According to Dr. Cambell (History of Arab Medicine), his principles of medical science surpassed those of Galen in the European medical curriculum.